Parity Filter Product – Winstar Series

This product was originally sold as an parity series. As a price-sensitive groups needs to repeat a large amount of analysis or filtration work every day, it is easy to incur a large amount of expenses over the years, so a superior quality at such a reasonable price filtration product is very needed. Therefore, analysts of specific requirements can choose our Winstar series by comparing corresponding parameters if necessary.

Requirements and features
Compared with Filstar, Winstar series has fewer types of film, less available pore diameter and diameter types, but they are the most commonly used types summarized in the laboratory. Therefore, it reduces costs and has a high cost-performance ratio .

Relevant parameters
Only parameters different from Filstar are described. No sterilization series, and one material and aperture in this series correspond to one color code design. Blue: PES membrane with 0.45um pore size; Yellow: PES membrane with 0.22um pore size; White: Nylon membrane with 0.45um pore size; Green: Nylon membrane with 0.22um pore size; Orange: Hydrophobic PEFE membrane with 0.45um pore size; Purple: Hydrophobic PEFE membrane with 0.22um pore size; Pink: Hydrophobic PEFE membrane with 0.45um pore size; Golden: Hydrophobic PEFE membrane with 0.22um pore size; Red: Hydrophilic PVDF membrane with 0.45um pore size; Black: Hydrophilic PVDF membrane with 0.22um pore size; Grey: Hydrophilic PVDF membrane with 0.45um pore size; Brown: Hydrophilic PVDF membrane with 0.22um pore size.

The Overview of Membrane Filter

What is Membrane Filter?
As a sterile inspection filter, the membrane filter can be utilized for two purposes. Besides, it also features two characteristics of the generality of cultivation methods. What is remarkable is that the filter is designed rationally with the glass material so that more stable chemical performance and stronger sealing could be provided. Successively, external contamination would be effectively forestalled, which ensures the bacteriological examination.

 
Characteristics
1 .Diverse Applications
a)To inject Chinese and Western medicines and process aseptic examinations for large infusion
b)To check microbe limitation(used for counting adventitious bacteria existing in personal Chinese and Western medicines, cosmetics, food, health products.etc)
c)To exam bacteria from body fluids, blood products and veterinary medicines clinically
d)To carry degerming filtration of small amounts of experimental materials.

2. Cultivation Methods
Operators can add the culture medium to glass tubes, which is directly used for enclosed cultivation, or take out the membrane filter to cultivate c, anaerobes and fungi in an ideal environment.

 
Certification
Membrane filters are generally certificated as required instruments by GMP of national drugs.

How to Store the Chromatography Column?

1.Prevent the generation of microorganisms from the buffer solution and the mobile phase of the aqueous solution, make sure that the mobile phase is used in a small amount, or add 200 ppm of sodium azide to the mobile phase of the water to inhibit bacterial growth (beware of its toxicity and potential explosiveness); or in the mobile phase Adding 20% of the organic modifier can also inhibit the growth of microorganisms. The organic modifier also helps to degas the mobile phase.

2.Store the column as much as possible in 100% organic solvent (Beiqing best) and avoid storing in buffer solution.

3.After the buffer solution was applied to the column, 15 to 20 column volumes of the same kind of water-organic solvent mobile phase containing no buffer were used to wash the column and then stored in a 100% organic solvent.

4.Avoid flushing tightly bonded C18 columns with purified water.

5.Twist the ends of the column with a plug to prevent the column bed packing from cracking.

Vacuum Filtration Manifolds

Starlab Scientific stocks a full variety of Vacuum Filtration Manifolds .

The material of Vacuum Filtration Manifolds are glass and stainless steel. There are three types of Vacuum Filtration Manifolds for glass series, one-way, three-way and six-way, as well for the stainless steel series. The integrative filter with reasonable structure and beautiful contour and without wedding spots, equipped with separate valve so that it can filter single sample or multiple samples at the same time so as to save time when testing a lot of samples.Starlab solvent filter made with 316L stainless steel has the characteristics of acid-resistance, alkali resistance, fast filtering speed, long service life, reasonable structure, easily cleaning and operating. It can be widely used in the fields of chemical industry, biochemical pharmacy, environmental protection, food and beverage etc.

All of Starlab Scientific’s Vacuum Filtration Manifolds are manufactured under ISO9001, and the strictly quality control system ensure variety of requirements from customers are met. Lots of good feedbacks from them encourage us to continue produce high-level pipettes.

Applications of Vacuum Pumps

Vacuum pumps are used in many industrial and scientific processes including composite plastic moulding processes, production of most types of electric lamps, vacuum tubes, and CRTs where the device is either left evacuated or re-filled with a specific gas or gas mixture, semiconductor processing, notably ion implantation, dry etch and PVD, ALD, PECVD and CVD deposition and so on in photolithography, electron microscopy, medical processes that require suction, uranium enrichment, medical applications such as radiotherapy, radiosurgery and radiopharmacy, analytical instrumentation to analyse gas, liquid, solid, surface and bio materials, mass spectrometers to create a high vacuum between the ion source and the detector, vacuum coating on glass, metal and plastics for decoration, for durability and for energy saving, such as low-emissivity glass, hard coating for engine components (as in Formula One), ophthalmic coating, milking machines and other equipment in dairy sheds, vacuum impregnation of porous products such as wood or electric motor windings, air conditioning service (removing all contaminants from the system before charging with refrigerant), trash compactor[citation needed], vacuum engineering, sewage systems (see EN1091:1997 standards), freeze drying, and fusion research. In the field of oil regeneration and rerefining, vacuum pumps create a low vacuum for oil dehydration and a high vacuum for oil purification.[12] Especially in the field of transformer maintenance, vacuum pumps play an essential role in transformer oil purification plants which are used to extend the lifetime of transformers in the field.[13]

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Vacuum may be used to power, or provide assistance to mechanical devices. In hybrid and diesel engine motor vehicles, a pump fitted on the engine (usually on the camshaft) is used to produce vacuum. In petrol engines, instead, vacuum is typically obtained as a side-effect of the operation of the engine and the flow restriction created by the throttle plate, but may be also supplemented by an electrically operated vacuum pump to boost braking assistance or improve fuel consumption. This vacuum may then be used to power the following motor vehicle components:[14] vacuum servo booster for the hydraulic brakes, motors that move dampers in the ventilation system, throttle driver in the cruise control servomechanism, door locks or trunk releases.

 

In an aircraft, the vacuum source is often used to power gyroscopes in the various flight instruments. To prevent the complete loss of instrumentation in the event of an electrical failure, the instrument panel is deliberately designed with certain instruments powered by electricity and other instruments powered by the vacuum source.

Starlab Flash Column Using Guidance

Prepacking the Flash Column

  • Remove the end fittings ;
  •  Eliminates the thermal effect from solvent adsorption on a dry cartridge;
  • Ensures pre-equilibrium between the solvent and the silica .
  • Entrapped air ,the thermal effect and lack of equilibrium can cause separation, purity and recovery  problems ,especially with early eluting compounds .
  • In general the recommended pre-equilibration volume is 3-5 column volumes prior to sample loading. If using gradient elution ,pre-equilibrate with the starting solvent mixture.

 

Sample Loading

  • Liquid loading: Each column is supplied with a built-in inserter which allows liquid injection via a syringe.
  • Dry loading: If internal dry loading is to be used,this inserter must be removed.
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Influencing SPE Cartridge Factor

There are several factors influencing the extraction efficiency:

(1) Packing (fixed phase)

Selecting the appropriate SPE column filler is the prerequisite for the ideal result.

(2) The strength of the solvent

1. With positive phase fixation, the strength of solvent increases with its polarity

2. With the reverse stationary phase, the strength of solvent increases with the weakening of the machine

(3) PH value

Ion exchange fixed phase, analyte and interference matter have different PKa. By adjusting the PH, the stationary phase can be charged with opposite charge and the interfering material has no charge. Or, in turn, the stationary phase is charged with the opposite charge, while the analyte does not carry the charge, thus achieving the purpose of separation and purification

Starlab QuEChERS Extraction Salt

Starlab QuEChERS Extraction Salt Packed with pre-weighed anhydrous extract salt, where anhydrous magnesium sulfate is used to remove moisture from the sample matrix and other buffers are used to provide the appropriate pH to ensure that some alkali-sensitive pesticides can Good recovery rate.

When a large sample of water content is encountered, the buffered salt reacts exothermically with water, thereby affecting the recovery rate. Starlab provides a separate extraction of salt packets, the user can join the organic solvent and then add the buffer salt, to prevent local overheating of the sample.

Features:

  •  Convenient packing and no contamination;
  •  All components are pre-accurate weighing,effectively improve the labor efficiency of the laboratory;
  •  Fully automated production, to eliminate the error of artificial packaging to ensure the repeat-ability of the analysis results.
  •  Extracted salt by special optimization, no impurity interference can ensure the recovery and sensitivity of multi-residue analysis.
  •  Easy to tear bag packaging. Easy to transport and storage, and can greatly reduce the use of cost.

Application:

  •  Sample extraction liquid purification;
  •  Food, environmental water samples and soil contaminants
  •   Analysis and validation of multi-residual pesticides in Vegetables and Fruits.

Method:

EU EN method and AOAC both available.

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Problem When Use HPLC

(1) Mobile phase: must be used after chromatography through the filter after use, and the mobile phase ratio can not be completely in accordance with the standard.

 

(2) Abnormal column pressure: the bubble inside the column, with the syringe to the bubble out, the column pressure back to normal. Column height: internal obstruction problems occur.

 

(3) Accuracy of external standard method: the accuracy of the external standard method related to the determination of the results, so the injection must be accurate results, the standard peak area RSD value should be less than 2.0. The general injector should not have bubbles present when extracting samples.

 

(4) When the test sample or standard peak pinning phenomenon, should check whether the phenomenon of collapse of the column occurred, if any, then re-column or change the new pillars.

HPLC chromatography Column Application ——-in the Detection of Drug

Life Science,health care and pharmaceutical were get more and more focuses by human beings as fast develop of scientific technique. In the drug analysis, high performance liquid chromatography is widely used in the quantitative analysis of drug analysis because of its specificity,.With feature of high sensitivity, fast and simple characteristics, especially in the interference factors show more superiority.

Determination of Lomefloxacin in Lomefloxacin Hydrochloride Eye Drops by HPLC Column; Column C, 0.02tool / nm Acid Solution (pH adjusted to 2.6 with triethylamine) – acetonitrile (R = 0.9998), the average recovery was 100.4, and the RSD0 of the repeated injection was in the range of 0.48 ~ 0.72 g, and the peak was 287 nm. .33 (n-6).

Zhang Min and other high-performance liquid chromatography with high-performance liquid chromatography determination of baicalin in addition to the domestic also on the quinolones antibiotics n, compound amoxicillin powder amoxicillin and clavulanic acid mouth, compound cold liquid, Qinlian Oral solution of baicalin, hydrobromide dextromethorphan tablets, feed chloropyridine, injection of neviomycin sulfate, small oxytetracycline C2b, health food in the sildenafil and celestium, plant more The injury of camptothecin and its derivatives, feed thirteen kinds of sulfonamides and other drugs were studied. In the use of high performance liquid chromatography for determination with other technologies, the detector is generally UV spectrophotometer, mass spectrometry and so on. These sophisticated detectors determine the sensitivity of the analysis, which is important for the analysis and is an important component of high performance liquid chromatography (HPLC).

Starlab HPLC column with ideal anti-pressure tube made from SS316 Stainless Steel can be wide chemical compatible for global users application.C18 Universal and C8 Universal especially equivalent to Waters brand,100 000 grade clean room made sorbents with perfect efficiency and 100% no contamination.

With development of pharmaceutical and R&D of chromatography,Starlab will keep on bring more columns to make more users satisfaction and do contribute to life science and pharmaceutical industries.

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